Introduction: Fake Manuscripts and the Paper-Mill Problem 1. 400,000 Fake Manuscripts and Counting: The Alarming Scale of the Paper-Mill Problem 2. Are These Manuscripts Really Fake? Exploring the Proportion of Paper-Mill Works 3. Unmasking the Frauds: The Role of Machine-Learning Software in Detecting Fake Manuscripts The Papermill Alarm: A Promising Tool in the Fight Against Fraudulent Science 4. The Power of Machine Learning: Adam Day’s Papermill Alarm Revolutionizes Detection 5. Cross-Publisher Initiative: The STM Integrity Hub Champions Fraud Detection Technology 6. From Concept to Reality: How the Papermill Alarm Is Helping Publishers Combat Fake Manuscripts Inside the Paper Mills: Understanding the Production of Fake Manuscripts 7. Factory of Fraud: The High-Speed Assembly Line of Fake Research Papers 8. Follow the Template: Identifying the Specific Patterns of Paper-Mill Studies 9. A Word and Image Shift: Analyzing the Techniques Used in Creating Fake Manuscripts Examining the Depth of the Problem: Using Data Analysis to Uncover the Truth 10. A Comprehensive Evaluation: Analyzing Titles and Abstracts to Detect Fake Manuscripts 11. 48 Million Papers and Beyond: The Massive Database Utilized in the Investigation 12. The Role of OpenAlex: Unveiling the Extent of the Paper-Mill Problem Identifying the Fraud Fighters: The Researchers Tackling Fake Manuscripts 13. Research-Integrity Sleuths: The Unsung Heroes in the Battle Against Fraudulent Science 14. Elisabeth Bik: The California Scientist on a Mission to Unmask Fake Manuscripts 15. David Bimler alias Smut Clyde: The New Zealand Researcher Exposing Fraudulent Practices Conclusion: Addressing the Paper-Mill Problem and Restoring Scientific Integrity 16. The Path Forward: Collaborative Efforts and Enhanced Prevention Strategies 17. Redefining Success: Moving Beyond Superficial Publication Metrics 18. Towards a Fraud-Free Future: The Imperative of Maintaining Scientific Integrity Related